Association between stunting and calcium intake in children with nephrotic syndrome

Ấn phẩm: Tạp chí DD&TP - Tập , Số Tập 21, 2E, Năm 2025, Năm 2025

Tác giả: Nguyễn Thị Thu Hậu, Nguyễn Thị Yến Vy, Võ Văn Tâm, Huỳnh Thị Vũ Quỳnh

Tóm tắt:

Tạp chí Dinh dưỡng & Thực phẩm - Tập 21, Số 2E, Năm 2025

(Link số tạp chí: https://tapchidinhduongthucpham.org.vn/index.php/jfns/issue/view/56)

Tác giả: Nguyễn Thị Thu Hậu, Nguyễn Thị Yến Vy, Võ Văn Tâm, Huỳnh Thị Vũ Quỳnh

Tóm tắt

Aims: To determine the association between stunting and calcium intake in children with nephrotic syndrome.

Methods: A cross-sectional study was conducted on 53 pediatric patients diagnosed with nephrotic syndrome at the Department of Nephrology - Endocrinology, Children Hospital No.2, from April 25 to June 26, 2022. Stunting and height faltering were classified according to the height-for-age and sex standards of World Health Organization. Calcium intake from the diet and medications was collected through dietary logs, prescription reviews, and calculated using the Eiyokun software, based on the Vietnamese food composition table and the recommended calcium intake by the Vietnamese National Institute of Nutrition. Other data such as blood albumin levels, disease duration, and corticosteroid resistance status were collected from medical treatment records.

Results: The prevalence of moderate stunting and severe stunting was 20.8% and 13.2%, respectively. The rate of height faltering was 30.2%. Fulfillment of the recommended daily calcium intake was 50.1% from diet alone and 75.5% after supplementation with medications. There was a significant association between stunting and calcium intake from diet at level >50% of the requirement (OR=0.28, p=0.001).

Conclusion: Stunting and height faltering were commonly observed in children with nephrotic syndrome at Children Hospital No.2. Those with calcium intake exceeding 50% of the daily requirement had a lower prevalence of stunting. It is essential to educate and counsel both the family and the children on appropriate nutrition, emphasizing the importance of adequate calcium intake from daily dietary sources.

Từ khóa: Nephrotic syndrome, stunting, height faltering, calcium intake

Tài liệu tham khảo

1. Vu Thi Chi, Ta Thi Thanh Phuong, Pham Trung Kien. Results of treatment of children with idiopathic nephrotic syndrome at Bac Ninh Obstetric and Children’s Hospital. Journal of Community Medicine. 2021;62(5):23-31.

2. Ndongo AA, Boiro D, Basse I, et al. Factors Affecting the Statural Growth Retardation in Children using Steroids in Idiopathic Nephrotic Syndrome. Asian Journal of Pediatric Research. 2021;7(4):70-76. Doi: 10.9734/ajpr/2021/v7i430225.

3. Nguyen Thi Le Thuy, Le Thy Phuong Anh, Hoang Thi Thuy Yen, Nguyen Thi Hong Duc. Electrolyte disorders in nephrotic syndrome in children. Ho Chi Minh City Journal of Medicine. 2018;22(4):50-55.

4. Soliman AT, Hamed N, De Sanctis V, et al. The Long-term (five years) Effects of Prednisone Therapy in Children with Frequently Relapsing Nephrotic Syndrome: A Controlled Study of Anthropometric Parameters and Metabolic Abnormalities. Acta Biomed. 2022; 93(5):e 2022303. Doi: 10.23750/abm.v93i5.13459.

5. Solari AUS, Motunrayo OA, et al. Nutritional assessment of children with nephrotic syndrome in a tertiary institution: A case controlled study. Trop J Nephrol. 2018;13(2):97-103.

6. WHO child growth standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. Geneva: World Health Organization; 2006. Retrieved from http://www.who.int/childgrowth/standards/technical_report/en/.

7. de Onis M, Onyango W A, Borghi E et al. Development of a WHO growth reference for school-aged children and adolescents. Bulletin of the World Health Organization. 2007;85:660-667. Laillou A, Wieringa F, Tran TN, et al. Hypovitaminosis D and mild hypocalcaemia are highly prevalent among young Vietnamese children and women and related to low dietary intake. PLoS One. 2013;8(5):e63979.doi: 10.1371/journal.pone.0063979.

8. Tran Thi Hong Minh, Nguyen Van Son. Evaluation of treatment outcomes for primary nephrotic syndrome in children in Thai Nguyen. Vietnam Journal of Medicine. 2023;16(5):23-31.

9. Hossain A, Mostafa G, Mannan KA, Deb KP, Hossain MM, Alam S. Correlation between serum albumin level and ionized calcium in idiopathic nephrotic syndrome in children. Urol Nephrol Open Access J. 2016; 3(2):111-115. Doi: 10.15406/unoaj.2016.03.00070.

10. Hussain N, Zello JA, Vasilevska-Ristovska J, et al. The rationale and design of Isight into Nephrotic Syndrome: Investigating Genes, Health and Therapeutics (INSIGHT): a prospective cohort study of childhood nephrotic syndrome. BMC nephrology. 2013:1-11. Doi: 10.1186/1471-2369-14-25.

Publication: Journal of Food and Nutrition Sciences - Volume , Number Tập 21, 2E, Năm 2025, Year 2025

Abstract:

Journal of Food and Nutrition Sciences - Vol.25, No.2E, Year 2025

(Link to the journal issue: https://tapchidinhduongthucpham.org.vn/index.php/jfns/issue/view/56)

Author: Thi Thu Hau NGUYEN, Thi Yen Vy NGUYEN, Van Tam VO, Thi Vu Quynh HUYNH

Abstract

Aims: To determine the association between stunting and calcium intake in children with nephrotic syndrome.

Methods: A cross-sectional study was conducted on 53 pediatric patients diagnosed with nephrotic syndrome at the Department of Nephrology - Endocrinology, Children Hospital No.2, from April 25 to June 26, 2022. Stunting and height faltering were classified according to the height-for-age and sex standards of World Health Organization. Calcium intake from the diet and medications was collected through dietary logs, prescription reviews, and calculated using the Eiyokun software, based on the Vietnamese food composition table and the recommended calcium intake by the Vietnamese National Institute of Nutrition. Other data such as blood albumin levels, disease duration, and corticosteroid resistance status were collected from medical treatment records.

Results: The prevalence of moderate stunting and severe stunting was 20.8% and 13.2%, respectively. The rate of height faltering was 30.2%. Fulfillment of the recommended daily calcium intake was 50.1% from diet alone and 75.5% after supplementation with medications. There was a significant association between stunting and calcium intake from diet at level >50% of the requirement (OR=0.28, p=0.001).

Conclusion: Stunting and height faltering were commonly observed in children with nephrotic syndrome at Children Hospital No.2. Those with calcium intake exceeding 50% of the daily requirement had a lower prevalence of stunting. It is essential to educate and counsel both the family and the children on appropriate nutrition, emphasizing the importance of adequate calcium intake from daily dietary sources.

Keywords: Nephrotic syndrome, stunting, height faltering, calcium intake

References